@article { ISI:000340414900005,
	title = {Effect of the branching pattern of hydrophobic dendrons on the core structure of linear-dendritic copolymer micelles},
	journal = {Macromolecular Chemistry and Physics},
	volume = {215},
	number = {15},
	year = {2014},
	month = {AUG},
	pages = {1456-1465},
	publisher = {WILEY-V C H VERLAG GMBH},
	type = {Article},
	address = {BOSCHSTRASSE 12, D-69469 WEINHEIM, GERMANY},
	abstract = {<p>Hydrophobic dendrons based on different branching patterns, viz. 3,5-di- and 3,4,5-trisubstituted phenyl rings, consist of the same backbone but exhibit different sizes, shapes, and hydrophobic densities. These dendrons are attached to poly(ethylene glycol) and the core properties of the copolymer micelles are investigated in tetrahydrofuran (THF)/water mixtures by neutron scattering. Two polymers with intermediate hydrophobicity are studied further with variations in the solvent composition and the temperature. The aggregation numbers for 3,4,5-based dendron copolymers are lower, with more THF molecules of solvation compared with the 3,5-based dendron copolymer, the difference being greater at higher generations due to different molecular shapes. The micellar core size increases in small steps with dendron size so that dye encapsulation is tuned.</p>},
	keywords = {diblock copolymers, linear-dendritic copolymers, micelles, neutron scattering, structure-property relations},
	issn = {1022-1352},
	doi = {10.1002/macp.201400150},
	author = {Kalva, Nagendra and Aswal, Vinod K. and Ambade, Ashootosh V.}
}
@article {49026,
	title = {Visible light and pH-responsive star copolymer and doxorubicin-polymer conjugate micelles for combination drug delivery and bioimaging},
	journal = {Journal of macromolecular science part A- pure and applied chemistry},
	volume = {61},
	year = {2024},
	month = {FEB },
	pages = {105-116},
	type = {Article},
	abstract = {<p>
	Amphiphilic 3-arm star copolymer containing visible light-cleavable BODIPY group and pH-responsive imine bonds at the junction of hydrophilic poly(ethylene glycol) (PEG) and two poly(epsilon-caprolactone) (PCL) arms was synthesized by the combination of ring-opening polymerization (ROP) and click chemistry. The formation and stimuli-responsive disruption of micelles were analyzed using dynamic light scattering and transmission electron microscopy. Dual stimuli-responsive release of anticancer drugs Doxorubicin (Dox) and Camptothecin (CPT) from the micelles was studied. Micellar assemblies containing Dox conjugated to PEG-BODIPY through imine bonds were prepared and controlled release of Dox in response to visible light and pH was shown. CPT and Dox-loaded star copolymer micelles as well as CPT loaded Dox-conjugated micelles were used in cellular uptake studies on MDA-MB 231 cells, and the synergistic effect of the two stimuli on the release of the two drugs was demonstrated inside the cells. Micellar assemblies also showed excellent bioimaging properties in the cellular uptake studies. [GRAPHICS]</p>
},
	keywords = {BODIPY, drug conjugate, micelles, pH-responsive, visible light-responsive},
	issn = {1060-1325},
	doi = {10.1080/10601325.2024.2302857},
	author = {Basutkar, Nitin B. and Surapaneni, Sai Geetika and Alam, Md. Shafi and Ambade, Ashootosh V.}
}
